Dysembryoplastic Neuroepithelial Tumor: MR Imaging Findings

PURPOSE: To describe the characteristic MR imaging findings of dysembryoplastic neuroepithelial tumor(DNT). MATERIALS & METHODS: We retrospectively reviewed MR images and pathologic findings of seven patients(five maleand two female, mean age 22) with surgically proven DNTs. We analyzed the location, size, configuration, signal intensity and contrast enhancement of nodules and accompanying calcifications, surrounding edema and calvarialchanges. RESULTS: All tumors were located in the cortical and subcortical portions of the temporal lobes. Most tumors showed small well-demarcated gyriform cystic nodules with almost the same signal intensity as that of the cerebrospinal fluid. Nodule margins were more sharply delineated on T2 than on T1-weighted images because on the former the peripheral portion of nodules shows high signal intensity. None of the patients showed surrounding edema or mass effect. On contrast-enhanced study, one of five patients showed subtle peripheral enhancement. Two patients showed included dense calcified nodules adjacent to cystic nodules, and two showed overlying calvarial thinning. CONCLUSION: Multiple small gyriform intracortical cystic nodules and occasional dense nodular calcifications are the characteristic findings of DNTs, and these may be differentiated from other focal lesion sin patients with temporal lobe epilepsy with the help of MR imaging.

Intranasal LH-RH treatment of cryptorchidism / 대한비뇨기과학회지

The effect of intranasal luteinizing hormone-releasing hormone (LH-RH) on cryptorchidism was investigated in 15 prepubertal boys with 26 undescended testes. Eleven patients were bilateral cryptorchidism. Boys with retractile testes, ectopic testes or palpable hernia, as well as boys who had chromosomal abnormalities were excluded from admission to the study. Synthetic LH-RH (Cryptocurs) was applied as nasal spray at a dose of 1.2mg daily over a period of 4 weeks. Testicular position and mobility were assessed independently by two investigator before and after 4 and I6 weeks of therapy. Testicular descent into the scrotum occurred in 5(19%) and partial descent in 10 testes (38%). Descended testes were bilateral cryptorchidism and located below the inguinal area in all cases. Follow-up examination 4 months after therapy showed no relapse. No side effects were observed. Overviewing the literature and regarding our own results, we believe that LH-RH has a place in the treatment of cryptorchidism. In the treatment of the more caudally positioned and bilateral undescended testes, it can be beneficial, because of the potential merits of avoiding an operation and the small number of minor side effects.